LL-37 5mg

Description

LL-37 is an antimicrobial peptide that belongs to the cathelicidin family and is encoded by the CAMP gene. It is the only cathelicidin found in humans and plays a crucial role in the innate immune system.

Structure and production:

LL-37 is produced as a precursor, hCAP-18, which is present in neutrophil granulocytes and epithelial cells. After proteolytic activation by enzymes such as kallikrein or proteinase 3, the active LL-37 peptide is formed.

Features:

+Antimicrobial activity: LL-37 has broad spectrum antimicrobial properties and is effective against various bacteria, viruses and fungi.

+Immunomodulation: In addition to direct antimicrobial effects, LL-37 modulates the immune system by regulating inflammatory responses and influencing the production of cytokines.

+Wound healing: LL-37 promotes wound healing by stimulating cell proliferation and angiogenesis.

Clinical relevance: Because of its versatile functions, LL-37 is being investigated for therapeutic applications, such as treating infections, inflammatory diseases and promoting wound healing. In addition, the potential of LL-37 as a biomarker for certain diseases is being investigated.

In summary, LL-37 is an essential peptide in the human immune system with diverse functions ranging from antimicrobial activity to immunomodulation and wound healing. It remains an important topic of research within medical science.